Sabinsa Corporation and Sami Labs founder Dr. Muhammed Majeed was lead author of a paper published on the cumulative safety data of ForsLean®, the company’s patented coleus forskohlii extract. Investigation of Acute, Sub-Acute, Chronic Oral Toxicity and Mutagenicity of Coleus forskohlii Briq. Hydroethanolic Extract was published in the International Journal Of Pharmacy & Pharmaceutical Research December 2015 Vol.:5, Issue:1.
The Paper concludes that there were no signs of toxicity in the repeated doses of 28 days (acute study) and 180 days (chronic study) with Coleus forskohlii (containing 10% forskolin). The repeated oral exposure to this extract up to 1000 mg/kg/day does not produce any toxic effects, hence considered to have ‘No Observed Adverse Effect Level’ (NOAEL) under the test conditions employed. Furthermore, ForsLean® exhibited a non-mutagenic response, thereby, showing it to be devoid of adverse effect on DNA of the organism.
"Coleus forskohlii root is a well-established ingredient with a long history of safety. Even for such well known herbs though, additions to the scientific literature are always welcome and this article serves to increase our understanding of the appropriate use of this important herb and its extracts,” said American Herbal Products Association President Michael McGuffin.
"While Sabinsa continues to innovate new efficacious ingredients, we are also committed to delivering the safest ingredients possible,” said Shaheen Majeed, Sabinsa’s Marketing Director. “Our award-winning ForsLean brand is set apart from other suppliers of Coleus forskohlii with our safety publications, patents, and human clinical studies. Substitutions just don’t have those advantages.”
International Journal of Pharmacy and Pharmaceutical Research (ijppr.humanjournals.com) is an open access, peer reviewed international monthly journal dedicated to the latest advancement in Pharmacy and Pharmaceutical Research. The Journal and Editorial Board endeavour to attract and publish articles from a variety of disciplines and educational settings to promote excellence in pharmaceutical research.
Sabinsa / Sami holds multiple patents on ForsLean internationally, including in the US, Canada, and the European Union. The company has an extensive cultivation program of coleus plants to insure a continuous supply of high quality raw material.
