Source
Curcuma longa (Turmeric)
Active components
Curcuminoids
Nutraceutical applications
Antioxidant
Anti-inflammatory support
Immune support
Plant part used
Roots
Patents
U.S. PATENT #5,861,415 (1999)
INTERNATIONAL PATENT: European Patent # EP0839037 (2002)
Beneficial Effects of Curcuminoids
- Curcumin C3 Complex® is an effective "Bioprotectant”, antioxidant quenching free radicals and also preventing their formation1
- Curcumin has been shown to be a COX-2 (Cyclooxygenase-2) inhibitor1
- Unlike conventional non steroidal anti-inflammatory drugs (NSAIDs), curcuminoids do not cause gastrointestinal side effects or ulcers
- Curcuminoids support a healthy immune system1
- Prevent connective tissue break down through inhibiting destructive enzymes2
Nutraceutical Applications of Curcuminoids
- Antioxidant support
- Alzheimer’s disease/dementia
- Cardiovascular support
- Immune support/Anti-tumor/Anticancer effects, Anti-inflammatory support
- Wound healing
- For example: Rheumatoid arthritis, postoperative inflammation, colorectal cancer, bladder cancer, oral leucoplakia, psoriasis, antiviral effects
Pharmacology & Clinical Trials
- Curcumin/Piperine - IND study approved: IND# 61,872
- Food & Drug Administration Office of Drug Evaluation I, Division of Oncology Drug Products
- The effects of Curcuminoids on aberrant crypt foci in the human colon: IND# 51,685
- UMDNJ- Robert Wood Johnson Medical School, New Jersey Cancer Institute
- Pilot study of curcuminoids with or without BioPerine® in patients with multiple myeloma: IND# 67,963
- MD Anderson Cancer Center, University of Texas
- Prevention and intervention ofAlzheimer's disease with curcuminoids: - University of California, Los Angeles
- Curcuminoids in patients with Lichen planus: IND#65,700/S-000 - University of California
- Phase IIa prevention study of C3 Complex® curcuminoids in women at increased risk for breast cancer
- MD Anderson Cancer Center, University of Texas
- The clinical and laboratory effects of topical curcuminoids in patients with normal skin and with dysplastic and benign nevi
- National Cancer Institute
- Phase II prevention study with C3 Complex® in patients with colorectal cancer stage I-III
- Lincoln Medical and Mental Health Center, Bronx, NY
- Phase I trial of C3 Complex® and precooperative patients with locally advanced esophageal or gastroesophageal carcinoma
- MD Anderson Cancer Center, University of Texas
- Metabolic studies and chemopreventive studies -University of Leicester, UK
